ID | 原文 | 译文 |
1313 | 研究表明,micRNAs(miRNA)突变或者异常会导致多种疾病,鉴定出与疾病相关的 microRNA 可以帮助诊断和治疗相关疾病。 | Studies show that mutations or abnormalities in micRNAs can lead to many diseases, and the identification of disease-associated microRNAs (miRNAs)can help diagnose and treat related diseases. |
1314 | 然而,通过生物实验方式获取准确关联关系,花费大,而且周期长。 | However, it is costly and long-term to obtain accurate correlations through biological experiments. |
1315 | 因此,本文中提出了一种基于网络内部拓扑信息的机器学习方法(HNDLM)预测疾病-miRNA 关联关系。 | Therefore, this paper proposes a machine learning method(HNDLM)that uses network topology information to predict disease-miRNA associations. |
1316 | HNDLM 避免搭建相似网络,而是将近年提出的 network embedding 方法应用在生物网络上。 | HNDLM avoids the construction of similarity networks, but applies the network embedding method proposed in recent years to biological networks. |
1317 | 实验结果显示,HNDLM 相较于 MIDPE,MIDP,WBSMDA,RLSMDA,CPTL,HDMP 经典算法在准确率和 AUC 值上效果更好。 | Experi-mental results show that HNDLM performs better than MIDPE, MIDP, WBSMDA, RLSMDA, CPTL, HDMP classical algo-rithms in accuracy and AUC value. |
1318 | 此外,在案例学习中,HNDLM 推荐的前 30 个候选 miRNAs,基本都能通过先前实验得到证实,HNDLM 能发现潜在疾病-miRNA 关系,有助于进一步研究疾病发病机制,推动生物信息学发展。 | In case study, the top 30 candidate miRNAs recommended by HNDLM can be confirmedby previous experiments. HNDLM can discover the potential disease-miRNA relationship and help to further study the patho-genesis of the disease, promote the development of bioinformatics. |
1319 | 能量兼容性会以电磁兼容性表象出现。 | Energy compatibility emerges as the surface phenomena of electromagnetic compatibility. |
1320 | 采用局限于电磁能量的理论和技术,可能会陷于技术困境或需要更高成本。 | With theories andtechnologies limited to electromagnetic energy, it may lead to technical dilemma or higher costs. |
1321 | 本文用能量兼容性及相关模型阐述电磁兼容性概念。 | The concept of EMC is stat-ed through energy compatibility and related models. |
1322 | 以机载雷达为例,初步分析论述能量兼容的电磁兼容性设计应用。 | The design of EMC with energy compatibility is preliminarily discussedby taking airborne radar as an example. |